TRiCoLOR is an efficient command-line application capable to accurately profile tandem repeats in error-prone long-read sequencing data. TRiCoLOR works on data both from Oxford Nanopore Technologies and Pacific Biosciences sequencers and is fast enough to be used on whole-genome alignments. TRiCoLOR offers:

1. A module suitable to identify repetitive regions de novo (SENSoR)
2. A module suitable to profile tandem repeats (REFER)
3. A module suitable to visualize tandem repeats (ApP)
4. A module suitable to check the mendelian consistency of tandem repeats in trio genomes sequencing data (SAGE)

All code is open-source and hosted on TRiCoLOR's GitHub page.

Contents:

1. Installation
2. General usage
3. Use cases

TIP

For questions, help or feature requests, please open an issue or get in touch with me at davidebolognini7@gmail.com

Citation

Are you using TRiCoLOR in your works? Please cite:

Davide Bolognini, Alberto Magi, Vladimir Benes, Jan O Korbel, Tobias Rausch. TRiCoLOR: tandem repeat profiling using whole-genome long-read sequencing data. GigaScience. 2020 Oct 7.